Seminars in Perinatology
Volume 34, Issue 4 , Pages 281-292 , August 2010

Delivery After Previous Cesarean: Long-Term Outcomes in the Child

  • T. Michael O'Shea, MD, MPH

      Affiliations

    • Department of Pediatrics (Neonatology), Wake Forest University, Health Sciences, Winston-Salem, NC
    • Corresponding Author InformationAddress reprint requests to T. Michael O'Shea, MD, MPH, Department of Pediatrics, Wake Forest University, Health Sciences, Medical Center Blvd, Winston-Salem, NC 27157
    • ,
  • Mark A. Klebanoff, MD, MPH

      Affiliations

    • Eunice Kennedy Shriver National Institute of Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD
    • ,
  • Caroline Signore, MD, MPH

      Affiliations

    • Eunice Kennedy Shriver National Institute of Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD

References 

  1. Harer WB. Vaginal birth after Cesarean delivery—Current status. JAMA. 2002;287:2627–2630
  2. Dodd JM, Crowther CA. Elective repeat Caesarean section versus induction of labour for women with a previous Caesarean birth. Cochrane Database Syst Rev Oct. 2006;18(4):CD004906
  3. Dodd JM, Crowther CA, Hiller JE, et al. Birth after Caesarean study—Planned vaginal birth or planned elective repeat Caesarean for women at term with a single previous Caesarean birth: Protocol for a patient preference study and randomised trial (BMC Pregnancy Childbirth, 2007). http://www.biomedcentral.com/1471-2393/7/17Accessed April 8, 2010
  4. Signore C, Klebanoff M. Neonatal morbidity and mortality after elective Cesarean delivery. Clin Perinatol. 2008;35:361
  5. Tita ATN, Landon MB, Spong CY, et al. Timing of elective repeat Cesarean delivery at term and neonatal outcomes. N Engl J Med. 2009;360:111U29
  6. Landon MB, Hauth JC, Leveno KJ, et al. Maternal and perinatal outcomes associated with a trial of labor after prior Cesarean delivery. N Engl J Med. 2004;351:2581–2589
  7. Chauhan SP, Martin JN, Henrichs CE, et al. Maternal and perinatal complications with uterine rupture in 142,075 patients who attempted vaginal birth after Cesarean delivery: A review of the literature. Am J Obstet Gynecol. 2003;189:408–417
  8. Spong CY, Landon MB, Gilbert S, et al. Risk of uterine rupture and adverse perinatal outcome at term after Cesarean delivery. Obstet Gynecol. 2007;110:801–807
  9. Guise JM, McDonagh MS, Osterweil P, et al. Systematic review of the incidence and consequences of uterine rupture in women with previous Caesarian section. BMJ. 2004;329:19–23
  10. Doumouchtsis SK, Arullkumaran S. Are all brachial plexus injuries caused by shoulder dystocia?. Obstet Gynecol Surv. 2009;64:615–623
  11. Lin PW, Stoll BJ. Necrotising enterocolitis. Lancet. 2006;368:1271–1283
  12. Ferriero DM. Medical progress—Neonatal brain injury. N Engl J Med. 2004;351:1985–1995
  13. Andersen J, Watt J, Olson J, et al. Perinatal brachial plexus palsy. Paediatr Child Health. 2006;11:93–100
  14. Badawi N, Felix JF, Kurinczuk JJ, et al. Cerebral palsy following term newborn encephalopathy: A population-based study. Dev Med Child Neurol. 2005;47:293–298
  15. Badawi N, Kurinczuk JJ, Keogh JM, et al. Intrapartum risk factors for newborn encephalopathy: The Western Australian case-control study. BMJ. 1998;317:1554–1558
  16. Felix JF, Badawi N, Kurinczuk JJ, et al. Birth defects in children with newborn encephalopathy. Dev Med Child Neurol. 2000;42:803–808
  17. Jacobs SE, Hunt R, Tarnow-Mordi WO, et al. Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev. 2007;CD003311-DOI:10:1002
  18. Graham EM, Ruis KA, Hartman AL, et al. A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy. Am J Obstet Gynecol. 2008;199:587–595
  19. Rahman J, Bhattee G, Rahman MS. Shoulder dystocia in a 16-year experience in a Teaching hospital. J Reprod Med. 2009;54:378–384
  20. MacKenzie IZ, Shah M, Lean K, et al. Management of shoulder dystocia—Trends in incidence and maternal and neonatal morbidity. Obstet Gynecol. 2007;110:1059–1068
  21. Mehta SH, Blackwell SC, Bujold E, et al. What factors are associated with neonatal injury following shoulder dystocia?. J Perinatol. 2006;26:85–88
  22. Chauhan SP, Christian B, Gherman RB, et al. Shoulder dystocia without versus with brachial plexus injury: A case-control study. J Matern Fetal Neonatal Med. 2007;20:313–317
  23. Gherman RB, Ouzounian JG, Kwok L, et al. Spontaneous vaginal delivery (A risk factor for Erb's palsy?). Am J Obstet Gynecol. 1998;178:423–427
  24. Foad SL, Mehlman CT, Foad MB, et al. Prognosis following neonatal brachial plexus palsy: An evidence-based review. J Child Orthop. 2009;[Epub ahead of print]
  25. Rouse DJ, Weiner SJ, Bloom SL, et al. Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network: Second-stage labor duration in nulliparous women: Relationship to maternal and perinatal outcomes. Am J Obstet Gynecol. 2009;201:357
  26. Alexander JM, Leveno KJ, Hauth J, et al. Fetal injury associated with Cesarean delivery. Obstet Gynecol. 2006;108:885–890
  27. Levine EM, Ghai V, Barton JJ, et al. Mode of delivery and risk of respiratory diseases in newborns. Obstet Gynecol. 2001;97:439–442
  28. Kolas T, Saugstad OD, Daltveit AK, et al. Planned Cesarean versus planned vaginal delivery at term: Comparison of newborn infant outcomes. Am J Obstet Gynecol. 2006;195:1538–1543
  29. Zanardo V, Simbi AK, Franzoi M, et al. Neonatal respiratory morbidity risk and mode of delivery at term: Influence of timing of elective Caesarean delivery. Acta Paediatr. 2004;93:643–647
  30. De Luca R, Boulvain M, Irion O, et al. Incidence of early neonatal mortality and morbidity after late-preterm and term Cesarean delivery. Pediatrics. 2009;123:E1064–E1071
  31. Hook B, Kiwi R, Amini SB, et al. Neonatal morbidity after elective repeat Cesarian section and trial of labor. Pediatrics. 1997;100:348–353
  32. Kamath BD, Todd JK, Glazner JE, et al. Neonatal outcomes after elective Cesarean delivery. Obstet Gynecol. 2009;113:1231–1238
  33. Ramachandrappa A, Jain L. Elective Cesarian section: Its impact on neonatal respiratory outcome. Clin Perinatol. 2008;35:373–393
  34. Finer N, Barrington KJ. Nitric oxide for respiratory failure in infants born at or near term. Cochrane Database Syst Rev. 2006;CD000399-DOI:10:1002/14651858
  35. Mugford M, Elbourne D, Field D. Extracorporeal membrane oxygenation for severe respiratory failure in newborn infants. Cochrane Database Syst Rev. 2008;CD001340-DOI:10:1002/14651858
  36. Truog WE, Kurth G, Haney B, et al. Hypoxic respiratory failure: Etiology and outcomes at one referral center 2000 through 2005. J Perinatol. 2007;27:371–374
  37. Thavagnanam S, Fleming J, Bromley A, et al. A meta-analysis of the association between Caesarian section and childhood asthma. Clin Exp Allergy. 2008;38:629–633
  38. Bager P, Wohlfahrt J, Westergaard T. Caesarean delivery and risk of atopy and allergic disesase: Meta-analyses. Clin Exp Allergy. 2008;38:634–642
  39. Tollanes MC, Moster D, Daltveit AK, et al. Cesarian section and risk of severe childhood asthma: A population-based cohort study. J Pediatr. 2008;153:112–116
  40. Aspberg S, Dahlquist G, Kahan T, et al. Is neonatal phototherapy associated with an increased risk for hospitalized childhood bronchial asthma?. Pediatr Allergy Immunol. 2007;18:313–319
  41. Roduit C, Scholtens S, de Jongste JC, et al. Asthma at 8 years of age in children born by caesarean section. Thorax. 2009;64:107–113
  42. Mallen CD, Mottram S, Wynne-Jones G, et al. Birth-related exposures and asthma and allergy in adulthood: A population-based cross-sectional study of young adults in North Staffordshire. J Asthma. 2008;45:309–312
  43. Pistiner M, Gold DR, Abdulkerim H, et al. Birth by Cesarian section, allergic rhinitis, and allergic sensitization among children with a parental history of atopy. J Allergy Clin Immunol. 2008;122:274–279
  44. Birnkrant DJ, Picone C, Markowitz W, et al. Association of transient tachypnea of the newborn and childhood asthma. Pediatr Pulmonol. 2006;41:978–984
  45. Ly NP, Ruiz-Perez B, Onderdonk AB, et al. Mode of delivery and cord blood cytokines: A birth cohort study. Clin Mol Allergy. 2006;4:13
  46. Gronlund MM, Lehtonen OP, Eerola E, et al. Fecal microflora in healthy infants born by different methods of delivery: Permanent changes in intestinal flora after Cesarean delivery. J Pediatr Gastroenterol Nutr. 1999;28:19–25
  47. Zhang J, Paré PD, Sandford AJ. Recent advances in asthma genetics. Respir Res. 2008;9:4
  48. Sadeghnejad A, Karmaus W, Arshad SH, et al. IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study. Respir Res. 2008;9:2
  49. Beghé B, Hall IP, Parker SG, et al. Polymorphisms in IL13 pathway genes in asthma and chronic obstructive pulmonary disease. Allergy. 2010;65:474–481
  50. Urry Z, Xystrakis E, Hawrylowicz CM. Interleukin-10-secreting regulatory T cells in allergy and asthma. Curr Allergy Asthma Rep. 2006;6:363–371
  51. Leung GM, Lam TH, Ho LM. Breast-feeding and its relation to smoking and mode of delivery. Obstet Gynecol. 2002;99:785–794
  52. Liston FA, Allen VM, O'Connell CM, et al. Neonatal outcomes with Caesarean delivery at term. Arch Dis Child Fetal Neonatal Ed. 2008;93:F176–F182
  53. Chien LY, Tai CJ. Effect of delivery method and timing of breastfeeding initiation on breastfeeding outcomes in Taiwan. Birth Issues Perinat Care. 2007;34:123–130
  54. Salam MT, Margolis HG, McConnell R, et al. Mode of delivery is associated with asthma and allergy occurrences in children. Ann Epidemiol. 2006;16:341–346
  55. Renz-Polster H, David MR, Buist AS, et al. Caesarian section delivery and the risk of allergic disorders in childhood. Clin Exp Allergy. 2005;35:1466–1472
  56. Eggesbo M, Botten G, Stigum H, et al. Is delivery by Cesarian section a risk factor for food allergy?. J Allergy Clin Immunol. 2003;112:420–426
  57. Cardwell CR, Stene LC, Joner G, et al. Caesarian section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: A meta-analysis of observational studies. Diabetologia. 2008;51:726–735
  58. Kramer MS, Chalmers B, Hodnett ED, et al. Promotion of breastfeeding intervention trial (PROBIT)—A randomized trial in the Republic of Belarus. JAMA. 2001;285:413–420
  59. Kramer MS, Matush L, Vanilovich I, et al. Effects of prolonged and exclusive breastfeeding on child height, weight, adiposity, and blood pressure at age 6.5 y: Evidence from a large randomized trial. Am J Clin Nutr. 2007;86:1717–1721
  60. Kramer MS, Aboud F, Mironova E, et al. Breastfeeding and child cognitive development—New evidence from a large randomized trial. Arch Gen Psychiatry. 2008;65:578–584
  61. Kramer MS, Matush L, Bogdanovich N, et al. Health and development outcomes in 6.5-y-old children breastfed exclusively for 3 or 6 mo. Am J Clin Nutr. 2009;90:1070–1074
  62. Kramer MS, Matush L, Vanilovich I, et al. A randomized breast-feeding promotion intervention did not reduce child obesity in Belarus. J Nutr. 2009;139:417S–421S
  63. Pearce N, Ait-Khaled N, Beasley R, et al. Worldwide trends in the prevalence of asthma symptoms: Phase III of the International study of asthma and allergies in childhood (Isaac). Thorax. 2007;62:758–766
  64. Chauhan SP, Rose CH, Gherman RB, et al. Brachial plexus injury: A 23-year experience from a tertiary center. Am J Obstet Gynecol. 2005;192:1795–1800
  65. Overland EA, Spydslaug A, Nielsen CS, et al. Risk of shoulder dystocia in second delivery: Does a history of shoulder dystocia matter?. Am J Obstet Gynecol. 2009;506:e1–e6
  66. Al Kubaisy W, Ali SH, Al Thamiri D. Risk factors for asthma among primary schoolchildren in Baghdad, Iraq. Saudi Med J. 2005;26:460–466
  67. Annesi-Maesano I, Moreau D, Strachan D. In utero and perinatal complications preceding asthma. Allergy. 2001;56:491–497
  68. Bager P, Melbye M, Rostgaard K, et al. Mode of delivery and risk of allergic rhinitis and asthma. J Allergy Clin Immunol. 2003;111:51–56
  69. Benn CS, Thorsen P, Jensen JS, et al. Maternal vaginal microflora during pregnancy and the risk of asthma hospitalization and use of antiasthma medication in early childhood. J Allergy Clin Immunol. 2002;110:72–77
  70. Calvani M, Alessandri C, Sopo SM, et al. Infectious and uterus related complications during pregnancy and development of atopic and nonatopic asthma in children. Allergy. 2004;59:99–106
  71. Debley JS, Smith JM, Redding GJ, et al. Childhood asthma hospitalization risk after Cesarean delivery in former term and premature infants. Ann Allergy Asthma Immunol. 2005;94:228–233
  72. Gessner BD, Chimonas MAR. Asthma is associated with preterm birth but not with small for gestational age status among a population-based cohort of Medicaid-enrolled children < 10 years of age. Thorax. 2007;62:231–236
  73. Hagendorens MM, Bridts CH, Lauwers K, et al. Perinatal risk factors for sensitization, atopic dermatitis and wheezing during the first year of life (PIPO study). Clin Exp Allergy. 2005;35:733–740
  74. Hakansson S, Kallen K. Caesarian section increases the risk of hospital care in childhood for asthma and gastroenteritis. Clin Exp Allergy. 2003;33:757–764
  75. Juhn YJ, Weaver A, Katusic S, et al. Mode of delivery at birth and development of asthma: A population-based cohort study. J Allergy Clin Immunol. 2005;116:510–516
  76. Kero J, Gissler M, Gronlund MM, et al. Mode of delivery and asthma—Is there a connection?. Pediatr Res. 2002;52:6–11
  77. Kurukulaaratchy RJ, Waterhouse L, Matthews SM, et al. Are influences during pregnancy associated with wheezing phenotypes during the first decade of life?. Acta Paediatr. 2005;94:553–558
  78. Maitra A, Sherriff A, Strachan D, et al. Mode of delivery is not associated with asthma or atopy in childhood. Clin Exp Allergy. 2004;34:1349–1355
  79. Mckeever TM, Lewis SA, Smith C, et al. Mode of delivery and risk of developing allergic disease. J Allergy Clin Immunol. 2002;109:800–802
  80. Metsala J, Kilkkinen A, Kaila M, et al. Perinatal factors and the risk of asthma in childhood—A population-based register study in Finland. Am J Epidemiol. 2008;168:170–178
  81. Nafstad P, Magnus P, Jaakkola JJK. Risk of childhood asthma and allergic rhinitis in relation to pregnancy complications. J Allergy Clin Immunol. 2000;106:867–873
  82. Negele K, Heinrich J, Borte M, et al. Mode of delivery and development of atopic disease during the first 2 years of life. Pediatr Allergy Immunol. 2004;15:48–54
  83. Oliveti JF, Kercsmar CM, Redline S. Pre- and perinatal risk factors for asthma in inner city African-American children. Am J Epidemiol. 1996;143:570–577
  84. Rusconi F, Galassi C, Forastiere F, et al. Maternal complications and procedures in pregnancy and at birth and wheezing phenotypes in children. Am J Respir Crit Care Med. 2007;175:16–21
  85. Vonk JM, Boezen HM, Postma DS, et al. Perinatal risk factors for bronchial hyperresponsiveness and atopy after a follow-up of 20 years. J Allergy Clin Immunol. 2004;114:270–276
  86. Werner A, Ramlau-Hansen CH, Jeppesen SK, et al. Caesarean delivery and risk of developing asthma in the offspring. Acta Paediatr. 2007;96:595–596
  87. Xu B, Pekkanen J, Hartikainen AL, et al. Caesarian section and risk of asthma and allergy in adulthood. J Allergy Clin Immunol. 2001;107:732–733
  88. Xu B, Pekkanen J, Jarvelin MR. Obstetric complications and asthma in childhood. J Asthma. 2000;37:589–594
  89. Chung W, Kim H, Nam CM. Breast-feeding in South Korea: Factors influencing its initiation and duration. Public Health Nutr. 2008;11:225–229
  90. Kohlhuber M, Rebhan B, Schwegler U, et al. Breastfeeding rates and duration in Germany: A Bavarian cohort study. Br J Nutr. 2008;99:1127–1132
  91. Perez-Rios N, Ramos-Valencia G, Ortiz AP. Cesarean delivery as a barrier for breastfeeding initiation: The Puerto Rican experience. J Hum Lact. 2008;24:293–302
  92. Theofilogiannakou M, Skouroliakou M, Gounaris A, et al. Breast-feeding in Athens, Greece: Factors associated with its initiation and duration. J Pediatr Gastroenterol Nutr. 2006;43:379–384
  93. Bernsen RMD, de Jongste JC, Koes BW, et al. Perinatal characteristics and obstetric complications as risk factors for asthma, allergy and eczema at the age of 6 years. Clin Exp Allergy. 2005;35:1135–1140
  94. Montgomery SM, Wakefield AJ, Morris DL, et al. The initial care of newborn infants and subsequent hay fever. Allergy. 2000;55:916–922
  95. Sugiyama M, Arakawa H, Ozawa K, et al. Early-life risk factors for occurrence of atopic dermatitis during the first year. Pediatrics. 2007;119:E716–E723

 Source of financial support: Dr Klebanoff was supported by Intramural Funds from the NIH, NICHD.

PII: S0146-0005(10)00032-7

doi: 10.1053/j.semperi.2010.03.008

Seminars in Perinatology
Volume 34, Issue 4 , Pages 281-292 , August 2010

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