Seminars in Perinatology
Volume 34, Issue 3 , Pages 183-187 , June 2010

Preterm Birth—An Emerging Risk Factor for Adult Hypertension?

  • Mikael Norman

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Mikael Norman, Professor of Pediatrics, Department of Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska Institute and University Hospital, S-141 86 Stockholm, Sweden

References 

  1. Wolf-Maier K, Cooper RS, Banegas JR, et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. J Am Med Assoc. 2003;289:2363–2369
  2. Barker DJ, Shiell AW, Barker ME, et al. Growth in utero and blood pressure levels in the next generation. J Hypertens. 2000;18:843–846
  3. Law CM, Shiell AW. Is blood pressure inversely related to birthweight? (The strength of evidence from a systematic review of the literature). J Hypertens. 1996;14:935–941
  4. Law CM, de Swiet M, Osmond C, et al. Initiation of hypertension in utero and its amplification throughout life. BMJ. 1993;306:24–27
  5. Goldenberg RL, Culhane JF, Iams JD, et al. Epidemiology and causes of preterm birth. Lancet. 2008;371:75–84
  6. Fellman V, Hellstrom-Westas L, Norman M, et al. One-year survival of extremely preterm infants after active perinatal care in Sweden. J Am Med Assoc. 2009;301:2225–2233
  7. Bonamy AK, Norman M, Kaijser M. Being born too small, too early, or both: Does it matter for risk of hypertension in the elderly?. Am J Hypertens. 2008;21:1107–1110
  8. Kaijser M, Bonamy AK, Akre O, et al. Perinatal risk factors for ischemic heart disease: Disentangling the roles of birthweight and preterm birth. Circulation. 2008;117:405–410
  9. Lawlor DA, Ronalds G, Clark H, et al. Birthweight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: Findings from the Aberdeen children of the 1950s prospective cohort study. Circulation. 2005;112:1414–1418
  10. Koupil I, Leon DA, Lithell HO. Length of gestation is associated with mortality from cerebrovascular disease. J Epidemiol Community Health. 2005;59:473–474
  11. Bonamy AK, Martin H, Jorneskog G, et al. Lower skin capillary density, normal endothelial function and higher blood pressure in children born preterm. J Intern Med. 2007;262:635–642
  12. Bracewell MA, Hennessy EM, Wolke D, et al. The EPICure study: Growth and blood pressure at 6 years of age following extremely preterm birth. Arch Dis Child Fetal Neonatal Ed. 2008;93:F108–F114
  13. Mikkola K, Leipala J, Boldt T, et al. Fetal growth restriction in preterm infants and cardiovascular function at five years of age. J Pediatr. 2007;151:494–4999:e1-e2
  14. Bayrakci US, Schaefer F, Duzova A, et al. Abnormal circadian blood pressure regulation in children born preterm. J Pediatr. 2007;151:399–403
  15. Edstedt BAK, Bengtsson J, Nagy Z, et al. Preterm birth and maternal smoking in pregnancy are strong risk factors for aortic narrowing in adolescence. Acta Paediatr. 2008;97:1080–1085
  16. Johansson S, Iliadou A, Bergvall N, et al. Risk of high blood pressure among young men increases with the degree of immaturity at birth. Circulation. 2005;112:3430–3436
  17. Bonamy AK, Bendito A, Martin H, et al. Preterm birth contributes to increased vascular resistance and higher blood pressure in adolescent girls. Pediatr Rev. 2005;58:845–849
  18. Pharoah PO, Stevenson CJ, West CR. Association of blood pressure in adolescence with birthweight. Arch Dis Child Fetal Neonatal Ed. 1998;79:F114–F118
  19. Doyle LW, Faber B, Callanan C, et al. Blood pressure in late adolescence and very low birthweight. Pediatrics. 2003;111:252–257
  20. Hack M, Schluchter M, Cartar L, et al. Blood pressure among very low birthweight (<1.5 kg) young adults. Pediatr Review. 2005;58:677–684
  21. Keijzer-Veen MG, Finken MJ, Nauta J, et al. Is blood pressure increased 19 years after intrauterine growth restriction and preterm birth? (A prospective follow-up study in the Netherlands). Pediatrics. 2005;116:725–731
  22. Hovi P, Andersson S, Eriksson JG, et al. Glucose regulation in young adults with very low birthweight. N Engl J Med. 2007;356:2053–2063
  23. Kistner A, Celsi G, Vanpee M, et al. Increased systolic daily ambulatory blood pressure in adult women born preterm. Pediatr Nephrol. 2005;20:232–233
  24. Rotteveel J, van Weissenbruch MM, Twisk JW, et al. Infant and childhood growth patterns, insulin sensitivity, and blood pressure in prematurely born young adults. Pediatrics. 2008;122:313–321
  25. Irving RJ, Belton NR, Elton RA, et al. Adult cardiovascular risk factors in premature babies. Lancet. 2000;355:2135–2136
  26. Johansson S, Norman M, Legnevall L, et al. Increased catecholamines and heart rate in children with low birthweight: Perinatal contributions to sympathoadrenal overactivity. J Intern Med. 2007;261:480–487
  27. Singhal A, Kattenhorn M, Cole TJ, et al. Preterm birth, vascular function, and risk factors for atherosclerosis. Lancet. 2001;358:1159–1160
  28. Evensen KA, Steinshamn S, Tjonna AE, et al. Effects of preterm birth and fetal growth retardation on cardiovascular risk factors in young adulthood. Early Hum Dev. 2009;85:239–245
  29. Singhal A, Cole TJ, Lucas A. Early nutrition in preterm infants and later blood pressure: Two cohorts after randomised trials. Lancet. 2001;357:413–419
  30. Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients (The Heart Outcomes Prevention Evaluation Study Investigators). N Engl J Med. 2000;342:145–153
  31. Law M, Wald N, Morris J. Lowering blood pressure to prevent myocardial infarction and stroke: A new preventive strategy. Health Technol Assess. 2003;7:1–94
  32. Bergvall N, Iliadou A, Johansson S, et al. Genetic and shared environmental factors do not confound the association between birthweight and hypertension: A study among Swedish twins. Circulation. 2007;115:2931–2938
  33. Armitage JA, Khan IY, Taylor PD, et al. Developmental programming of the metabolic syndrome by maternal nutritional imbalance: How strong is the evidence from experimental models in mammals?. J Physiol. 2004;561:355–377
  34. Roseboom TJ, van der Meulen JH, van Montfrans GA, et al. Maternal nutrition during gestation and blood pressure in later life. J Hypertens. 2001;19:29–34
  35. Godfrey KM, Lillycrop KA, Burdge GC, et al. Epigenetic mechanisms and the mismatch concept of the developmental origins of health and disease. Pediatr Rev. 2007;61:5R–10R
  36. Ozanne SE, Constancia M. Mechanisms of disease: The developmental origins of disease and the role of the epigenotype. Nat Clin Pract Endocrinol Metab. 2007;3:539–546
  37. Waterland RA, Jirtle RL. Transposable elements: Targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol. 2003;23:5293–5300
  38. Weaver IC, Cervoni N, Champagne FA, et al. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7:847–854
  39. Norman M. Low birthweight and the developing vascular tree: A systematic review. Acta Paediatr. 2008;97:1165–1172
  40. Abitbol CL, Ingelfinger JR. Nephron mass and cardiovascular and renal disease risks. Semin Nephrol. 2009;29:445–454
  41. Nuyt AM, Alexander BT. Developmental programming and hypertension. Curr Opin Nephrol Hypertens. 2009;18:144–152
  42. Matthews SG. Early programming of the hypothalamo-pituitary-adrenal axis. Trends Endocrinol Metab. 2002;13:373–380
  43. Cohen G, Vella S, Jeffery H, et al. Cardiovascular stress hyperreactivity in babies of smokers and in babies born preterm. Circulation. 2008;118:1848–1853
  44. Doyle LW. Cardiopulmonary outcomes of extreme prematurity. Semin Perinatol. 2008;32:28–34
  45. Kapoor A, Petropoulos S, Matthews SG. Fetal programming of hypothalamic-pituitary-adrenal (HPA) axis function and behavior by synthetic glucocorticoids. Brain Res Rev. 2008;57:586–595
  46. Dalziel SR, Walker NK, Parag V, et al. Cardiovascular risk factors after antenatal exposure to betamethasone: 30-Year follow-up of a randomised controlled trial. Lancet. 2005;365:1856–1862
  47. Finken MJ, Keijzer-Veen MG, Dekker FW, et al. Antenatal glucocorticoid treatment is not associated with long-term metabolic risks in individuals born before 32 weeks of gestation. Arch Dis Child Fetal Neonatal Ed. 2008;93:F442–F447
  48. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics. 2004;114(2 Suppl 4th Report):555–576

PII: S0146-0005(10)00023-6

doi: 10.1053/j.semperi.2010.02.009

Seminars in Perinatology
Volume 34, Issue 3 , Pages 183-187 , June 2010

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