Seminars in Perinatology
Volume 34, Issue 1 , Pages 28-38, February 2010

Cranial Ultrasonography in Neonates: Role and Limitations

Division of neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands

In experienced hands, cranial ultrasonography (cUS) is an excellent tool to detect the most frequently occurring brain abnormalities in preterm and full-term neonates, to study the evolution of lesions, and to follow brain maturation. It enables screening of the brain and serial imaging in high-risk neonates. However, cUS also has limitations and magnetic resonance imaging is needed in most neonates with (suspected) parenchymal brain injury and/or neurological symptoms and in very preterm infants. In this review, we discuss the applications, possibilities, indications, predictive value, and limitations of neonatal cUS. We will pay attention to the standard cUS procedure and expand on optimizing the possibilities of cUS by using supplemental acoustic windows and changing transducers and focus points. For illustration numerous cUS images are provided.

Keywords: neonate, brain, cranial ultrasonography

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 Lara M. Leijser was supported by a grant from ZonMw, the Netherlands Organisation for Health Research and Development (grant number 920-03-388).

PII: S0146-0005(09)00090-1

doi:10.1053/j.semperi.2009.10.002

Seminars in Perinatology
Volume 34, Issue 1 , Pages 28-38, February 2010