Seminars in Perinatology
Volume 33, Issue 3 , Pages 138-142 , June 2009

The Management of Severe Hypertension

  • Laura A. Magee, MD, MSc, FRCPC, FACP

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    • Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada
    • Centre for Applied Health Research and Evaluation, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    • Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada
    • Corresponding Author InformationAddress reprint requests to Laura A. Magee, MD, MSc, FRCPC, FACP, BC Women's Hospital and Health Centre, 4500 Oak Street, Room 1U59, Vancouver, BC V6P 1S8, Canada
    • ,
  • Peter von Dadelszen, MBChB, DPhil, FRANZCOG, FRCSC, FRCOG

      Affiliations

    • Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, British Columbia, Canada
    • Centre for Applied Health Research and Evaluation, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    • Department of Health Care and Epidemiology, University of British Columbia, Vancouver, British Columbia, Canada

References 

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  3. Rey E, Le Lorier J, Burgess E, et al. Report of the Canadian Hypertension Society Consensus Conference (3. Pharmacologic treatment of hypertensive disorders in pregnancy). CMAJ. 1997;157:1245–1254
  4. Lower SA, Brown MA, Dekker G, et al. Guidelines for the management of hypertensive disorders of pregnancy 2008. www.somanz.org
  5. Magee LA, Helewa M, Rey E, et al. SOGC clinical practice guideline: Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy. J Obstet Gynaecol Can. 2008;30:S1–S48
  6. Golara M, Jones C, Randhawa M, et al. Inflationary oscillometric blood pressure monitoring: Validation of the Omron-MIT. Blood Press Monit. 2002;7:325–328
  7. Reinders A, Cuckson AC, Lee JT, et al. An accurate automated blood pressure device for use in pregnancy and pre-eclampsia: The Microlife 3BTO-A. Br J Obstet Gynaecol. 2005;112:915–920
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  9. Villar J, Say L, Shennan A, et al. Methodological and technical issues related to the diagnosis, screening, prevention, and treatment of pre-eclampsia and eclampsia. Int J Gynecol Obstet. 2004;85(Suppl 1):S28–S41
  10. Martin JN, Thigpen BD, Moore RC, et al. Stroke and severe preeclampsia and eclampsia: A paradigm shift focusing on systolic blood pressure. Obstet Gynecol. 2005;105:246–254
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  12. Lindenstrom E, Boysen G, Nyboe J. Influence of systolic and diastolic blood pressure on stroke risk: A prospective observational study. Am J Epidemiol. 1995;142:1279–1290
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  16. Magee LA, Cham C, Waterman EJ, et al. Hydralazine for treatment of severe hypertension in pregnancy: Meta-analysis. Br Med J. 2003;327:955–960
  17. Duley L, Henderson-Smart DJ. Drugs for treatment of very high blood pressure during pregnancy. Cochrane Database Syst Rev. 2002;4:CD001449
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  19. Tuffnell DJ, Jankowicz D, Lindow SW, et al. Outcomes of severe pre-eclampsia/eclampsia in Yorkshire 1999/2003. Br J Obstet Gynaecol. 2005;112:875–880
  20. Brown MA, Buddle ML, Farrell T, et al. Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. Am J Obstet Gynecol. 2002;187:1046–1050
  21. Magee LA, Cote AM, von Dadelszen P. Nifedipine for severe hypertension in pregnancy: Emotion or evidence?. J Obstet Gynaecol Can. 2005;27:260–262
  22. Magee LA, Miremadi S, Li J, et al. Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia. Am J Obstet Gynecol. 2005;193:153–163
  23. Duley L, Farrell B, Spark P, et al. Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? (The magpie trial: A randomised placebo-controlled trial). Lancet. 2002;359:1877–1890
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  26. Mroczek WJ, Lee WR, Davidov ME. Effect of magnesium sulfate on cardiovascular hemodynamics. Angiology. 1977;28:720–724
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  29. Cetin A, Yurtcu N, Guvenal T, et al. The effect of Glyceryl trinitrate on hypertension in women with severe preeclampsia, HELLP syndrome, and eclampsia. Hypertens Pregnancy. 2004;23:37–46
  30. Neri I, Valensise H, Facchinetti F, et al. 24-hour ambulatory blood pressure monitoring: A comparison between transdermal glyceryl-trinitrate and oral nifedipine. Hypertens Pregnancy. 1999;18:107–113
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  33. Sass N, Itamoto CH, Silva MP, et al. Does sodium nitroprusside kill babies? (A systematic review). Sao Paulo Med J. 2007;125:108–111
  34. Magee L, Sadeghi S. Prevention and treatment of postpartum hypertension. Cochrane Database Syst Rev. 2005;1:CD004351
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  36. Waterman EJ, Magee LA, Lim KI, et al. Do commonly used oral antihypertensives alter fetal or neonatal heart rate characteristics? (A systematic review). Hypertens Pregnancy. 2004;23:155–169
  37. Ganzevoort W, Rep A, Bonsel GJ, et al. A randomised controlled trial comparing two temporising management strategies, one with and one without plasma volume expansion, for severe and early onset pre-eclampsia. Br J Obstet Gynaecol. 2005;112:1358–1368
  38. Magee LA, Ornstein MP, von Dadelszen P. Fortnightly review: Management of hypertension in pregnancy. Br Med J. 1999;318:1332–1336
  39. Confidential Enquiry into Maternal and Child Health: Why Mothers Die 2000-2002. London: RCOG; 2004;

PII: S0146-0005(09)00005-6

doi: 10.1053/j.semperi.2009.02.001

Seminars in Perinatology
Volume 33, Issue 3 , Pages 138-142 , June 2009

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