Seminars in Perinatology
Volume 31, Issue 4 , Pages 204-207, August 2007

Implantation and Early Embryonic Development: Implications for Pregnancy

  • Danielle Vitiello, PhD, MD
  • ,
  • Pasquale Patrizio, MD, MBE

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Pasquale Patrizio, MD, MBE, Yale University School of Medicine, Yale Fertility Center, Department of Obstetrics, Gynecology and Reproductive Sciences, 150 Sargeant Drive, New Haven, CT 06511.

Yale University Fertility Center, Department of Obstetrics, Gynecology and Reproductive Sciences, New Haven, CT.

Implantation represents the limiting step in governing reproductive outcomes. The process is driven by both embryo and endometrium alike. Minute perturbations in this orchestration lay foundation for pregnancy-associated complications that may manifest throughout the gestational course. Furthermore, placental function dictates many aspects of fetal development inclusive of preeclampsia and intrauterine growth restriction (IUGR). Novel techniques such as Multigate Spectral Doppler Analysis (MSDA) may allow for early detection and diagnosis of potentially deleterious fetal outcomes.

Keywords: implantation, placenta, intrauterine growth restriction (IUGR), Multigate Spectral Doppler Analysis (MSDA)

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PII: S0146-0005(07)00065-1

doi:10.1053/j.semperi.2007.05.006

Seminars in Perinatology
Volume 31, Issue 4 , Pages 204-207, August 2007