Seminars in Perinatology
Volume 30, Issue 2 , Pages 81-88 , April 2006

The Near-Term (Late Preterm) Human Brain and Risk for Periventricular Leukomalacia: A Review

  • Hannah C. Kinney, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Hannah C. Kinney, MD, Department of Pathology, Enders 1112, Children’s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115.

References 

  1. Inder TE , Warfield SK , Wang H , et al.   Abnormal cerebral structure is present at term in premature infants . Pediatrics . 2005;115:286–294
  2. Valleur D , Magny JF , Rigourd V , et al.   Mid and long-term neurological prognosis of preterm infants less than 28 weeks gestational age . J Gynecol Obstet Biol Reprod (Paris) . 2004;33(suppl 1):S72–S78
  3. van Baar AL , van Wassenaer AG , Briet JM , et al.   Very preterm birth is associated with disabilities in multiple developmental domains . J Pediatr Psychol . 2005;30:247–255
  4. Volpe JJ . Cerebral white matter injury in the premature infant (more common than you think) . Pediatrics . 2003;112:176–180
  5. Kinney HC , Haynes RL , Folkerth RD . White matter lesions in the perinatal period . In:  Golden JA ,  Harding B editor. Pathology and Genetics (Acquired and Inherited Diseases of the Developing Nervous System) . Basel: ISN Neuropathology Press; 2004;p. 156–170
  6. Pierson CR , Folkerth RD , Haynes RL , et al.   Gray matter injury in premature infants with or without periventricular leukomalacia (PVL) . J Neuropathol Exp Neurol . 2004;62:5
  7. Kinney HC , Panigrahy A , Newburger JW , et al.   Hypoxic ischemic brain injury in infants with congenital heart disease dying after cardiac surgery . Acta Neuropathol (Berl) . 2005;110:563–578
  8. Galli KK , Zimmerman RA , Jarvik GP , et al.   Periventricular leukomalacia is common after neonatal cardiac surgery . J Thorac Cardiovasc Surg . 2004;127:692–704
  9. Mahle WT , Tavani F , Zimmerman RA , et al.   An MRI study of neurological injury before and after congenital heart surgery . Circulation . 2002;106(suppl 12):I109–I114
  10. Guihard-Costa AM , Larroche JC . Differential growth between the fetal brain and its infratentorial part . Early Hum Dev . 1990;23:27–40
  11. Huppi PS , Warfield S , Kikinis R , et al.   Quantitative magnetic resonance imaging of brain development in premature and mature newborns . Ann Neurol . 1998;43:224–235
  12. Kinney HC , Armstrong DL . Perinatal neuropathology . In:  Graham DI ,  Lantos PE editor. Greenfield’s Neuropathology . (ed 7). London: Arnold; 2002;p. 557–559
  13. Haynes RL , Borenstein NS , DeSilva TM , et al.   Axonal development in the cerebral white matter of the human fetus and infant . J Comp Neurol . 2005;484:156–167
  14. Back SA , Luo NL , Borenstein NS , et al.   Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury . J Neurosci . 2001;21:1302–1312
  15. Back SA , Luo NL , Borenstein NS , et al.   Arrested oligodendrocyte lineage progression during human cerebral white matter development (dissociation between the timing of progenitor differentiation and myelinogenesis) . J Neuropathol Exp Neurol . 2002;61:197–211
  16. Brody BA , Kinney HC , Kloman AS , et al.   Sequence of central nervous system myelination in human infancy. I. An autopsy study of myelination . J Neuropathol Exp Neurol . 1987;46:283–301
  17. Kinney HC , Brody BA , Kloman AS , et al.   Sequence of central nervous system myelination in human infancy. II. Patterns of myelination in autopsied infants . J Neuropathol Exp Neurol . 1988;47:217–234
  18. Kinney HC , Karthigasan J , Borenshteyn NI , et al.   Myelination in the developing human brain (biochemical correlates) . Neurochem Res . 1994;19:983–996
  19. McQuillen PS , Ferriero DM . Perinatal subplate neuron injury (implications for cortical development and plasticity) . Brain Pathol . 2005;15:250–260
  20. Ghosh A , Antonnini A , McConnell SK , et al.   Requirement for subplate neurons in the formation of thalamocortical connections . Nature . 1990;347:179–181
  21. Ghosh A , Shatz CJ . A role for subplate neurons in the patterning of connections from thalamus to neocortex . Development . 1993;117:1031–1047
  22. Hanganu IL , Kilb W , Luhmann HJ . Functional synaptic projections on subplate neurons in neonatal rat somatosensory cortex . Cereb Cortex . 2001;11:400–410
  23. Ghosh A . Subplate neurons and the patterning of thalamocortical connections . Ciba Found Symp . 1995;193:150–172
  24. Kanold PO , Kara P , Reid RC , et al.   Role of subplate neurons in functional maturation of visual cortical columns . Science . 2003;301:521–525
  25. Kostovic I , Rakic P . Developmental history of the transient subplate zone in the visual and somatosensory cortex of the macaque monkey and human brain . J Comp Neurol . 1990;297:441–470
  26. Samuelsen GB , et al.   The changing number of cells in the human fetal forebrain and its subdivisions (a stereological analysis) . Cereb Cortex . 2003;13:115–122
  27. Rakic S , Secevic N . Programmed cell death in the developing human telencephalon . Eur J Neurosci . 2000;12:2721–2734
  28. Simonati A , Rosso T , Rizzuto N . DNA fragmentation in normal development of the human central nervous system (a morphological study during corticogenesis) . Neuropathol Appl Neurobiol . 1997;23:203–211
  29. McQuillen PS , Sheldon RA , Shatz CJ , et al.   Selective vulnerability of subplate neurons after early neonatal hypoxia-ischemia . J Neurosci . 2003;23:3308–3315
  30. Marin-Padilla M . Developmental neuropathology and impact of perinatal brain damage. II. White matter lesions of the neocortex . J Neuropathol Exp Neurol . 1997;56:219–235
  31. Inder TE , Wells SJ , Mogridge NB , et al.   Defining the nature of the cerebral abnormalities in the premature infant (a qualitative magnetic resonance imaging study) . J Pediatr . 2003;143:171–179
  32. Inder TE , Huppi PS , Warfield S , et al.   Periventricular white matter injury in the premature infant is followed by reduced cerebral cortical gray matter volume at term . Ann Neurol . 1999;46:755–760
  33. Aggleton JP , Mishkin M . Visual recognition impairment following medial thalamic lesions in monkeys . Neuropsychologia . 1983;21:189–197
  34. Himmelmann K , Hagberg G , Beckung E , et al.   The changing panorama of cerebral palsy in Sweden. IX. Prevalence and origin in the birth-year period 1995-1998 . Acta Pediatr . 2005;94:287–294
  35. De Vries LS , et al.   Neurological, electrophysiological and MRI abnormalities in infants with extensive cystic leukomalacia . Neuropediatrics . 1987;18:61–66
  36. Iida K , et al.   Immunocytochemical study of myelination and oligodendrocytes in infants with periventricular leukomalacia . Pediatr Neurol . 1995;13:296–304
  37. Haynes RL , Folkerth RD , Keefe RJ , et al.   Nitrative and oxidative injury to premyelinating oligodendrocytes in periventricular leukomalacia . J Neuropathol Exp Neurol . 2003;62:441–450
  38. Haynes RL , Baud O , Li J , et al.   Oxidative and nitrative injury in periventricular leukomalacia (a review) . Brain Pathol . 2005;15:216–224
  39. Back SA , Gan X , Li Y , et al.   Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by gluthatione depletion . J Neurosci . 1998;18:6241–6243
  40. Folkerth RD , Haynes RL , Borenstein N , et al.   Developmental lag of superoxide dismutases relative to other antioxidant enzymes in premyelinated human telencephalic white matter . J Neuropathol Exp Neurol . 2004;14:265–274
  41. Follett PL , Deng W , Dai W , et al.   Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia (a protective role for topiramate) . J Neurosci . 2004;24:4412–4420
  42. DeSilva TM , Kinney HC , Volpe JJ , et al.   Glutamate transporter expression in cerebral white matter of the developing human brain . Washington, D.C: Society for Neuroscience; 2002; Program No. 44.8. 2002 Abstract Viewer/Itinerary Planner
  43. Billiards SS , Haynes RL , Folkerth RD , et al.   Development of microglia in the cerebral white matter of the human fetus and infant . J Comp Neurol . 2005; in press

PII: S0146-0005(06)00043-7

doi: 10.1053/j.semperi.2006.02.006

Seminars in Perinatology
Volume 30, Issue 2 , Pages 81-88 , April 2006

Article Tools

* Image Usage & Resolution